Godfrey T E
Calif Med. 1971 Oct;115(4):1-4.
Mithramycin (Mithracin(R)) rapidly controlled the hypercalcemia of malignant disease in every patient. This control was temporary, and intermittent administration of the antibiotic was required.Hypercalcemia frequently responds to non-toxic maneuvers such as hydration and moderate doses of corticoids. Until the mechanism of action of Mithramycin in hypercalcemia is better understood, caution should be urged in its prolonged use for this purpose.
光辉霉素(普卡霉素)能迅速控制每位恶性疾病患者的高钙血症。这种控制是暂时的,需要间歇性使用抗生素。高钙血症通常对诸如补液和中等剂量皮质类固醇等无毒措施有反应。在光辉霉素治疗高钙血症的作用机制得到更好理解之前,应谨慎长期使用该药用于此目的。