光辉霉素治疗恶性疾病引起的高钙血症。
Mithramycin for hypercalcemia of malignant disease.
作者信息
Godfrey T E
出版信息
Calif Med. 1971 Oct;115(4):1-4.
Abstract
Mithramycin (Mithracin(R)) rapidly controlled the hypercalcemia of malignant disease in every patient. This control was temporary, and intermittent administration of the antibiotic was required.Hypercalcemia frequently responds to non-toxic maneuvers such as hydration and moderate doses of corticoids. Until the mechanism of action of Mithramycin in hypercalcemia is better understood, caution should be urged in its prolonged use for this purpose.
摘要
光辉霉素（普卡霉素）能迅速控制每位恶性疾病患者的高钙血症。这种控制是暂时的，需要间歇性使用抗生素。高钙血症通常对诸如补液和中等剂量皮质类固醇等无毒措施有反应。在光辉霉素治疗高钙血症的作用机制得到更好理解之前，应谨慎长期使用该药用于此目的。
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本文引用的文献
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Hypercalcemia in neoplastic disease.肿瘤性疾病中的高钙血症。
Cancer. 1956 Nov-Dec;9(6):1135-40. doi: 10.1002/1097-0142(195611/12)9:6<1135::aid-cncr2820090611>3.0.co;2-6.
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Hypercalcemia of malignant disease.恶性肿瘤引起的高钙血症
Calif Med. 1967 Jul;107(1):54-61.
3
Effect of mithramycin on calcium and hydroxyproline metabolism in patients with malignant disease.光辉霉素对恶性疾病患者钙和羟脯氨酸代谢的影响。
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Mithramycin treatment of malignant hypercalcaemia.光辉霉素治疗恶性高钙血症。
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5
Mithramycin treatment of hypercalcemia.光辉霉素治疗高钙血症。
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