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我们应该计划针对细菌性脑膜炎进行普遍的儿童期疫苗接种吗?

Should we plan a general childhood vaccination against bacterial meningitis?

作者信息

Mäkelä P H, Peltola H

出版信息

Dev Biol Stand. 1979;43:61-7.

PMID:42596
Abstract

An estimation of the benefits of vaccination against bacterial meningitis are based on the age-specific incidence of meningitis caused by the different groups of meningococci, by Haemophilus influenzae and by pneumococci, and the known efficacy of the present polysaccharide vaccines against these agents. Since the incidence of bacterial meningitis is more than ten times higher below the age of five years that at a later age, vaccination at 1 1/2 years of age could prevent a large fraction of all cases.

摘要

针对细菌性脑膜炎疫苗接种益处的评估,是基于不同组别的脑膜炎球菌、流感嗜血杆菌和肺炎球菌所引起的脑膜炎在特定年龄的发病率,以及现有多糖疫苗针对这些病原体的已知效力。由于五岁以下儿童细菌性脑膜炎的发病率比五岁及以上人群高出十倍以上,因此1.5岁时接种疫苗可以预防大部分病例。

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