Burke R M, Schwartz L P, Snider D E
Am J Public Health. 1979 Apr;69(4):340-7. doi: 10.2105/ajph.69.4.340.
Following a retrospective review of tuberculosis cases reported from Ottawa County, Oklahoma, from 1969 through 1973, a selective tuberculosis screening project was implemented. Screening of a "target group" of the population, 519 former miners, greater than or equal to 50 years of age, resulted in the discovery of abnormal chest X-rays in 182; (103 with silicosis, 36 with silicotuberculosis, 12 with inactive tuberculosis, and 31 with other abnormalities). Eighty-five of these persons had positive tuberculin skin tests. Preventive therapy was recommended for 50, and 36 completed the prescribed course of treatment. Eight new bacteriologically confirmed cases of tuberculosis were found and treated. A large number of persons (1,904) residing in the same area who were not part of the target group were also screened for tuberculosis. This group contained a large number of positive tuberculin reactors but very few were candidates for isoniazid preventive therapy. Thirteen persons in this group had abnormal chest X-rays consistent with inactive tuberculosis but 12 had been identified and given preventive therapy before the project began. These data suggest that selective approaches to screening for tuberculosis in a community which are based on an in-depth retrospective review of the tuberculosis case register can be highly successful.
在对俄克拉荷马州渥太华县1969年至1973年报告的结核病病例进行回顾性审查之后,实施了一项选择性结核病筛查项目。对519名年龄大于或等于50岁的前矿工这一“目标人群”进行筛查,结果发现182人的胸部X光片异常;(103人患有矽肺病,36人患有矽肺结核,12人患有非活动性结核病,31人有其他异常)。这些人中85人结核菌素皮肤试验呈阳性。建议对50人进行预防性治疗,36人完成了规定疗程的治疗。发现并治疗了8例新的经细菌学确诊的结核病病例。还对居住在同一地区但不属于目标人群的大量人员(1904人)进行了结核病筛查。该组中有大量结核菌素反应阳性者,但很少有人适合接受异烟肼预防性治疗。该组中有13人的胸部X光片异常,符合非活动性结核病表现,但其中12人在项目开始前已被识别并接受了预防性治疗。这些数据表明,基于对结核病病例登记册进行深入回顾性审查的社区结核病选择性筛查方法可能会非常成功。