Paradise J L, Smith C G
Ann Otol Rhinol Laryngol. 1979 Jan-Feb;88(1 Pt 1):56-65. doi: 10.1177/000348947908800110.
As a test for detecting middle ear disease among preschool children, tympanometry -- as opposed to audiometry -- has three advantageous attributes: a high degree of sensitivity, minimal need for subject cooperation, and total objectivity. For these reasons interest has arisen in tympanometry as a method for screening, i.e., identifying children with previously undetected middle ear disease. However, uncertainty persists concerning the importance of detecting apparently asymptomatic middle ear effusions, and concerning optimal methods, or even the advisability, of treating them. Further, the sensitivity and specificity of tympanometry depend on how the pass-fail cutoff point is defined. Defining this cutoff point so as to achieve high sensitivity may result in excessively low specificity, with the production of large numbers of false-positives who then become overreferrals. Data are presented to show how the validity of the test may be increased to some extent by attention to the gradient of "negative-pressure" tympanograms. At the present time, given the various aforementioned uncertainties, and with adequate validation as to the presence or absence of disease often lacking in reported studies of impedance screening in preschool populations, the cumulative results of these studies do not warrant embarking on large-scale screening programs. What is needed instead is additional research to explore the issue further.
作为一种检测学龄前儿童中耳疾病的测试方法,与听力测定法相比,鼓室声导抗测试具有三个优势:高度敏感性、受试者配合需求最小以及完全客观性。由于这些原因,鼓室声导抗测试作为一种筛查方法,即识别先前未被检测出中耳疾病的儿童,已引起人们的关注。然而,对于检测明显无症状的中耳积液的重要性、最佳治疗方法,甚至治疗的可取性,仍存在不确定性。此外,鼓室声导抗测试的敏感性和特异性取决于通过-失败临界值的定义方式。将该临界值定义为实现高敏感性可能会导致特异性过低,产生大量假阳性结果,进而导致过度转诊。本文提供的数据表明,通过关注“负压”鼓室图的梯度,测试的有效性可在一定程度上提高。目前,鉴于上述各种不确定性,且在学龄前人群阻抗筛查的报道研究中,对疾病存在与否往往缺乏充分验证,这些研究的累积结果并不足以开展大规模筛查项目。相反,需要进一步开展研究以深入探讨该问题。