Weiss G B, Nienhuis A W, McIntosh C L, Klein H G
Arch Intern Med. 1979 Mar;139(3):374-5. doi: 10.1001/archinte.139.3.374.
Severe, traumatic, cardiac, hemolytic anemia developed in a patient nine years after mitral valve replacement with a Starr-Edwards model 6120 prosthesis. Cardiac catheterization failed to demonstrate a perivalvular leak or prosthetic malfunction. Transfusion on two occasions resulted in accelerated hemolysis and failed to maintain an appreciable elevation of the hemoglobin level. At operation, a perivalvular leak was found. Replacement of the valve led to complete resolution of the hemolytic problem. The case demonstrates that cardiac hemolysis may be a good indicator of valve dysfunction.
一名患者在使用斯塔尔-爱德华兹6120型假体进行二尖瓣置换术后九年出现严重的创伤性心脏溶血性贫血。心导管检查未能显示瓣膜周围漏血或假体故障。两次输血均导致溶血加速，且未能维持血红蛋白水平的明显升高。手术时发现瓣膜周围漏血。更换瓣膜后溶血问题完全解决。该病例表明心脏溶血可能是瓣膜功能障碍的一个良好指标。
