维生素K依赖性羧化酶：可溶性肽羧化的要求及底物特异性。 - Suppr

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超能文献

Vitamin K-dependent carboxylase: requirements for carboxylation of soluble peptide and substrate specificity.

作者信息

Suttie J W, Lehrman S R, Geweke L O, Hageman J M, Rich D H

出版信息

Biochem Biophys Res Commun. 1979 Feb 14;86(3):500-7. doi: 10.1016/0006-291x(79)91742-x.

DOI:10.1016/0006-291x(79)91742-x

PMID:426799

Abstract

摘要

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Functional Study of the Vitamin K Cycle Enzymes in Live Cells.活细胞中维生素K循环酶的功能研究

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A new model for vitamin K-dependent carboxylation: the catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine.维生素K依赖性羧化作用的新模型：使维生素K对苯二酚去质子化的催化碱不是半胱氨酸，而是活化胺。

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Osteocalcin binds tightly to the gamma-glutamylcarboxylase at a site distinct from that of the other known vitamin K-dependent proteins.骨钙素在一个与其他已知维生素K依赖性蛋白不同的位点紧密结合γ-谷氨酰羧化酶。

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Expression of bovine vitamin K-dependent carboxylase activity in baculovirus-infected insect cells.牛维生素K依赖性羧化酶活性在杆状病毒感染昆虫细胞中的表达。

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On the mechanism of the anticlotting action of vitamin E quinone.关于维生素E醌抗凝血作用的机制。

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