用抗精神病药物五氟利多治疗的哺乳期母亲4周龄后代的学习缺陷。 - Suppr

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Learning deficits in 4 weeks old offspring of the nursing mothers treated with the neuroleptic drug penfluridol.

作者信息

Ahlenius S, Brown R, Engel J, Lundborg P

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1973;279(1):31-7. doi: 10.1007/BF00502065.

DOI:10.1007/BF00502065

PMID:4270737

Abstract

摘要

相似文献

Learning deficits in 4 weeks old offspring of the nursing mothers treated with the neuroleptic drug penfluridol.用抗精神病药物五氟利多治疗的哺乳期母亲4周龄后代的学习缺陷。

Naunyn Schmiedebergs Arch Pharmacol. 1973;279(1):31-7. doi: 10.1007/BF00502065.

Regional changes in monoamine levels and in the rate of tyrosine and tryptophan hydroxylation in 4 week old offspring of nursing mothers treated with the neuroleptic drug penfluridol.用抗精神病药物五氟利多治疗的哺乳期母亲4周龄后代中，单胺水平以及酪氨酸和色氨酸羟化速率的区域变化。

Naunyn Schmiedebergs Arch Pharmacol. 1974;282(4):327-34. doi: 10.1007/BF00500982.

The influence of haloperidol and penfluridol on the learning capacity of the schizophrenic.氟哌啶醇和五氟利多对精神分裂症患者学习能力的影响。

Arzneimittelforschung. 1974 Jul;24(7):1072-4.

Reduced turnover in mesolimbic dopamine neurons in 4-week-old offspring of nursing mothers treated with penfluridol.用五氟利多治疗的哺乳期母亲的4周龄后代中脑边缘多巴胺神经元的更新减少。

Brain Res. 1976 Jul 9;110(2):407-12. doi: 10.1016/0006-8993(76)90417-0.

The influence of various neuroleptic drugs on shock avoidance responding in rats. 3. Amphetamine antagonism in the discriminated Sidman avoidance procedure.各种抗精神病药物对大鼠回避休克反应的影响。3. 辨别性西德曼回避程序中的苯丙胺拮抗作用。

Psychopharmacologia. 1970;17(2):151-9. doi: 10.1007/BF00402705.

Clopimozide (R 29 764), a new highly potent and orally long-acting neuroleptic of the diphenylbutylpiperidine series.氯哌莫齐（R 29 764），一种新型高效且口服长效的二苯基丁基哌啶系列抗精神病药。

Arzneimittelforschung. 1975 Aug;25(8):1287-94.

Pimozide treatment of chronic schizophrenics as compared with haloperidol and penfluridol maintenance treatment. A multidisciplinary approach.与氟哌啶醇和五氟利多维持治疗相比，匹莫齐特治疗慢性精神分裂症患者。一种多学科方法。

Acta Psychiatr Belg. 1972 Mar;72(2):199-214.

The pharmacology of penfluridol (R 16341) a new potent and orally long-acting neuroleptic drug.五氟利多（R 16341）——一种新型强效口服长效抗精神病药物的药理学

Eur J Pharmacol. 1970 Jul 15;11(2):139-54. doi: 10.1016/0014-2999(70)90043-9.

[Acquisition of active behavior in rats due to small doses of piperidyl-benzylates].[小剂量哌啶基苄酯导致大鼠出现主动行为]

Vojnosanit Pregl. 1972 Mar;29(3):151-4.

Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia.五氟利多：一种长效口服抗精神病药，用作慢性精神分裂症的治疗药物。

Curr Ther Res Clin Exp. 1974 Oct;16(10):1041-58.

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Presence of chlorprothixene and its metabolites in breast milk.氯丙硫蒽及其代谢物在母乳中的存在情况。

Eur J Clin Pharmacol. 1984;27(5):611-3. doi: 10.1007/BF00556901.

Naunyn Schmiedebergs Arch Pharmacol. 1974;282(4):327-34. doi: 10.1007/BF00500982.

Secretion of the gastrokinetic agent cisapride in human milk.促胃肠动力药西沙必利在人乳中的分泌情况。

Eur J Clin Pharmacol. 1986;30(6):735-6. doi: 10.1007/BF00608226.

Milk concentrations of flupenthixol, nortriptyline and zuclopenthixol and between-breast differences in two patients.两名患者的氟哌噻吨、去甲替林和氯普噻吨的乳汁浓度及双侧乳房差异。

Eur J Clin Pharmacol. 1988;35(2):217-20. doi: 10.1007/BF00609257.

Long-term behavioural and biochemical effects following prolonged treatment with a neuroleptic drug (flupenthixol) in rats.大鼠长期使用抗精神病药物（氟哌噻吨）治疗后的长期行为和生化影响。

Psychopharmacology (Berl). 1977 Oct 20;54(2):203-8. doi: 10.1007/BF00426781.

Antagonism by d-amphetamine of learning deficits in rats induced by exposure to antipsychotic drugs during early postnatal life.右旋苯丙胺对出生后早期暴露于抗精神病药物所致大鼠学习缺陷的拮抗作用。

Naunyn Schmiedebergs Arch Pharmacol. 1975;288(2-3):185-93. doi: 10.1007/BF00500526.

本文引用的文献

Storage synthesis, and metabolism of monoamines in the developing brain.发育中大脑中单胺的储存、合成及代谢

J Neurochem. 1962 Jan-Feb;9:53-8. doi: 10.1111/j.1471-4159.1962.tb07492.x.

Serotonin content of rat brain in relation to sex and age.大鼠大脑中血清素含量与性别和年龄的关系。

J Neurochem. 1960 Feb;5:202. doi: 10.1111/j.1471-4159.1960.tb13355.x.

TOXICITY OF PSYCHOTHERAPEUTIC DRUGS.精神治疗药物的毒性

Practitioner. 1965 Jan;194:72-84.

Learning deficits of offspring after administration of tranquilizing drugs to the mothers.母亲服用镇静药物后子代的学习缺陷。

Nature. 1963 Jan 5;197:106-7. doi: 10.1038/197106a0.

Amine oxidase and 5-hydroxytryptamine in developing rat brain.发育中大鼠大脑中的胺氧化酶和5-羟色胺

J Neurochem. 1960 Sep;6:99-104. doi: 10.1111/j.1471-4159.1960.tb13455.x.

Changes in monoamines of rat brain during postnatal ontogeny.大鼠出生后个体发育过程中脑内单胺的变化。

Biochim Biophys Acta. 1966 Dec 28;130(2):511-3. doi: 10.1016/0304-4165(66)90247-9.

Prenatal chlorpromazine effects on liver, survival and behavior of mice offspring.产前使用氯丙嗪对小鼠后代肝脏、生存及行为的影响。

J Pharmacol Exp Ther. 1966 Jan;151(1):110-25.

Effect of injection of tranquillizing drugs during pregnancy on offspring.孕期注射镇静药物对后代的影响。

Nature. 1965 Mar 13;205(976):1070-2. doi: 10.1038/2051070a0.

Schedule of appearance of 5-hydroxy-tryptamine (serotonin) and associated enzymes in the developing rat brain.5-羟色胺（血清素）及相关酶在发育中大鼠大脑中的出现时间表。

J Neurochem. 1965 Nov;12(11):911-8. doi: 10.1111/j.1471-4159.1965.tb11934.x.

Unexpected adrenergic effects of chlorpromazine: eating elicited by injection into rat hypothalamus.氯丙嗪意外的肾上腺素能效应：注射到大鼠下丘脑引发进食行为。

Science. 1969 Aug 8;165(3893):609-11. doi: 10.1126/science.165.3893.609.

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