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视网膜色素上皮界面。

The retinal-pigment epithelial interface.

作者信息

Foulds W S

出版信息

Br J Ophthalmol. 1979 Feb;63(2):71-84. doi: 10.1136/bjo.63.2.71.

DOI:10.1136/bjo.63.2.71
PMID:427074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1043402/
Abstract

The interdependence of the outer retina and pigment epithelium is illustrated by the functional changes and structural alterations which occur in each in response to choroidal ischaemia, retinal detachment, vitamin A deficiency, and other causes. The pluripotential role of the pigment epithelium is stressed, particularly in relation to the phagocytosis of outer segment material and the ability of this layer to undergo metaplasia into a variety of different cell types. Similarities of all disturbances of the retinal-pigment epithelial interface to retinitis pigmentosa are pointed out, and the significance of the findings in relation to this disease is discussed.

摘要

外层视网膜与色素上皮之间的相互依存关系，体现在各自因脉络膜缺血、视网膜脱离、维生素A缺乏及其他病因所发生的功能变化和结构改变中。着重强调了色素上皮的多能作用，尤其是其对外节段物质的吞噬作用，以及该层发生化生成为多种不同细胞类型的能力。指出了视网膜-色素上皮界面所有病变与色素性视网膜炎的相似之处，并讨论了这些发现与该疾病的相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/fa3696b27f56/brjopthal00206-0012-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/e38c045c72d1/brjopthal00206-0002-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/11e5b90e63e7/brjopthal00206-0005-b.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/911e598b18e6/brjopthal00206-0011-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/e38c045c72d1/brjopthal00206-0002-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/4880f5e74279/brjopthal00206-0003-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/64b5f52b80e6/brjopthal00206-0003-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/f54a2e83c5cc/brjopthal00206-0004-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/b1eb9d328df4/brjopthal00206-0005-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/11e5b90e63e7/brjopthal00206-0005-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/ea0e50af23f4/brjopthal00206-0006-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/56a5a5dd9493/brjopthal00206-0006-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/911e598b18e6/brjopthal00206-0011-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ac/1043402/fa3696b27f56/brjopthal00206-0012-a.jpg

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引用本文的文献

1
Analysis of RPE morphometry in human eyes.人眼视网膜色素上皮形态测量分析。
Mol Vis. 2016 Jul 30;22:898-916. eCollection 2016.
2
The standing potential of the eye in retinal detachments.视网膜脱离时眼睛的静息电位。
Doc Ophthalmol. 1981 Mar 20;50(2):337-42. doi: 10.1007/BF00158018.

本文引用的文献

1
Malformation of the erythrocytes in a case of atypical retinitis pigmentosa.非典型色素性视网膜炎病例中的红细胞畸形。
Blood. 1950 Apr;5(4):381-87.
2
EXPERIMENTAL RETINAL DETACHMENT.实验性视网膜脱离
Trans Ophthalmol Soc U K (1962). 1963;83:153-70.
3
THE ULTRASTRUCTURE OF THE PIGMENT EPITHELIUM AND OF THE PHOTORECEPTOR-PIGMENT EPITHELIUM JUNCTION IN THE HUMAN RETINA.人类视网膜色素上皮及光感受器-色素上皮连接的超微结构
J Ultrastruct Res. 1963 Dec;41:484-96. doi: 10.1016/s0022-5320(63)80080-5.
4
OBSERVATIONS ON THE ROD AND CONE LAYER OF THE HUMAN RETINA. A LIGHT AND ELECTRON MICROSCOPIC STUDY.关于人类视网膜视杆和视锥层的观察。一项光镜和电镜研究。
Invest Ophthalmol. 1963 Oct;2:446-59.
5
Studies on the endoplasmic reticulum. V. Its form and differentiation in pigment epithelial cells of the frog retina.内质网的研究。V. 蛙视网膜色素上皮细胞中的内质网形态与分化
J Biophys Biochem Cytol. 1960 Sep;8(1):181-205. doi: 10.1083/jcb.8.1.181.
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Chemistry of visual adaptation in the rat.大鼠视觉适应的化学过程
Nature. 1960 Oct 8;188:114-8. doi: 10.1038/188114a0.
7
Histochemical studies on photoreceptor cells.光感受器细胞的组织化学研究。
Ann N Y Acad Sci. 1959 Nov 12;74(2):182-95. doi: 10.1111/j.1749-6632.1958.tb39543.x.
8
Acid mucopolysaccharide in the retinal pigment epithelium and visual cell layer of the developing mouse eye.发育中小鼠眼睛视网膜色素上皮和视觉细胞层中的酸性粘多糖
Am J Ophthalmol. 1959 Jan;47(1 Pt 2):488-98; discussion 498-9. doi: 10.1016/s0002-9394(14)78054-7.
9
Choriocapillaris and lamina elastica (vitrea) of the rat eye.大鼠眼睛的脉络膜毛细血管层和弹性层（玻璃体）。
Br J Ophthalmol. 1967 Sep;51(9):599-616. doi: 10.1136/bjo.51.9.599.
10
Participation of the retinal pigment epithelium in the rod outer segment renewal process.视网膜色素上皮在视杆细胞外段更新过程中的参与。
J Cell Biol. 1969 Aug;42(2):392-403. doi: 10.1083/jcb.42.2.392.