Gruenewald B, Nicola C U, Lustig A, Schwarz G, Klump H
Biophys Chem. 1979 Jan;9(2):137-47. doi: 10.1016/0301-4622(79)87008-8.
Ultrasonic absorption and velocity dispersion curves have been measured in the temperature induced helix-coil transition range of poly-N5-(3-hydroxypropyl)-L-glutamine in a methanol/water mixture. The results clearly reflect an effect due to the kinetics of the conformational conversion. A practically single relaxation time is observed which passes through a maximum when plotted versus the degree of transition. This maximum occurs at definitely less than 50% helix as predicted for by the theory for the comparatively short chain length involved here. The results are discussed in relation to previous theoretical and experimental findings.
在甲醇/水混合物中，对聚-N5-(3-羟丙基)-L-谷氨酰胺温度诱导的螺旋-线圈转变范围内的超声吸收和速度色散曲线进行了测量。结果清楚地反映了构象转变动力学所产生的影响。观察到一个几乎单一的弛豫时间，当它与转变程度作图时会出现一个最大值。这个最大值出现时的螺旋度肯定小于50%，正如这里所涉及的相对较短链长的理论所预测的那样。结合先前的理论和实验结果对这些结果进行了讨论。
