Suppr超能文献

来自昆虫飞行肌肉的钙依赖性肌球蛋白。

Calcium-dependent myosin from insect flight muscles.

作者信息

Lehman W, Bullard B, Hammond K

出版信息

J Gen Physiol. 1974 May;63(5):553-63. doi: 10.1085/jgp.63.5.553.

Abstract

Calcium regulation of the insect actomyosin ATPase is associated with the thin filaments as in vertebrate muscles, and also with the myosin molecule as in mollusks. This dual regulation is demonstrated using combinations of locust thin filaments with rabbit myosin and locust myosin with rabbit actin; in each case the ATPase of the hybrid actomyosin is calcium dependent. The two regulatory systems are synergistic, the calcium dependency of the locust actomyosin ATPase being at least 10 times that of the hybrid actomyosins described above. Likewise Lethocerus myosin also contains regulatory proteins. The ATPase activity of Lethocerus myosin is labile and is stabilized by the presence of rabbit actin. Tropomyosin activates the ATPase of insect actomyosin and the activation occurs irrespective of whether the myosin is calcium dependent or rendered independent of calcium.

摘要

昆虫肌动球蛋白ATP酶的钙调节与脊椎动物肌肉一样与细肌丝有关,也与软体动物一样与肌球蛋白分子有关。使用蝗虫细肌丝与兔肌球蛋白以及蝗虫肌球蛋白与兔肌动蛋白的组合证明了这种双重调节;在每种情况下,杂种肌动球蛋白的ATP酶都依赖钙。这两种调节系统是协同的,蝗虫肌动球蛋白ATP酶的钙依赖性至少是上述杂种肌动球蛋白的10倍。同样,田鳖肌球蛋白也含有调节蛋白。田鳖肌球蛋白的ATP酶活性不稳定,兔肌动蛋白的存在可使其稳定。原肌球蛋白激活昆虫肌动球蛋白的ATP酶,无论肌球蛋白是否依赖钙或变得不依赖钙,这种激活都会发生。

相似文献

10
Paratropomyosin, a new myofibrillar protein, weakens rigor linkages formed between actin and myosin.
J Biochem. 1987 Nov;102(5):1187-92. doi: 10.1093/oxfordjournals.jbchem.a122157.

引用本文的文献

2
To understand muscle you must take it apart.要了解肌肉,你必须将其分解。
Front Physiol. 2014 Mar 11;5:90. doi: 10.3389/fphys.2014.00090. eCollection 2014.

本文引用的文献

8
Force measurements in skinned muscle fibres.对去表皮肌纤维的力测量。
J Physiol. 1969 Feb;200(3):807-19. doi: 10.1113/jphysiol.1969.sp008723.
10
Calcium ion and muscle contraction.钙离子与肌肉收缩。
Prog Biophys Mol Biol. 1968;18:123-83. doi: 10.1016/0079-6107(68)90023-0.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验