Selitrennikoff C P, Nelson R E, Siegel R W
Genetics. 1974 Oct;78(2):679-90. doi: 10.1093/genetics/78.2.679.
Two new mutant genes in Neurospora crassa prevent the formation of free macroconidia from proconidial chains. These genes, called conidial separation-1 and conidial separation-2, are phase-specific, playing no role in either the sexual life cycle or other aspects of the asexual life cycle. A cell-wall-associated autolytic activity was found to increase in wild-type cultures at the time of active formation of free conidia from proconidial chains; no such increase was detected in mutant cultures. It appears that the products of these genes are both essential for and unique to macroconidiation.
粗糙脉孢菌中的两个新突变基因可阻止从分生孢子链形成游离的大分生孢子。这些基因被称为分生孢子分离-1和分生孢子分离-2,具有阶段特异性,在有性生活周期或无性生命周期的其他方面均不起作用。在野生型培养物中,当从分生孢子链中活跃形成游离分生孢子时,发现一种与细胞壁相关的自溶活性会增加;而在突变体培养物中未检测到这种增加。看来这些基因的产物对于大分生孢子形成既是必需的也是独特的。