Gelberg H J, Brundage B H, Glantz S, Parmley W W
Circulation. 1979 May;59(5):991-1000. doi: 10.1161/01.cir.59.5.991.
We were interested in divising a relatively simple quantitative technique that could be used on a routine clinical basis for wall motion analysis. Three quantitative methods of left ventricular (LV) regional analysis were compared in the 30 degrees right anterior oblique and 60 degrees left anterior oblique projection. The control group consisted of 17 patients with qualitatively normal LV wall motion; the abnormal group comprised 17 patients with at least one region of severe, qualitative wall motion abnormality. Normal regional values were determined for area, chord and radial methods by applying the techniques to the ventriculograms of the control group. Each technique was then applied to the abnormal group's ventriculograms to determine the percentage of qualitatively abnormal regions not detected by each method. The area method had the lowest failure rate (p less than 0.001) and the best separation of measured normal and abnormal regions' ejection changes (p less than 0.001), and best reflected symmetric uniform motion of the ventricular silhouette. We conclude that the area method, of the techniques examined, was best for the quantitative analysis of LV wall motion abnormalities.
我们致力于设计一种相对简单的定量技术，该技术可在常规临床基础上用于壁运动分析。在右前斜30度和左前斜60度投影中比较了三种左心室（LV）区域分析的定量方法。对照组由17例左心室壁运动定性正常的患者组成；异常组包括17例至少有一个区域存在严重定性壁运动异常的患者。通过将这些技术应用于对照组的心室造影图，确定面积、弦长和径向方法的正常区域值。然后将每种技术应用于异常组的心室造影图，以确定每种方法未检测到的定性异常区域的百分比。面积法的失败率最低（p<0.001），测量的正常和异常区域射血变化的分离效果最佳（p<0.001），并且最能反映心室轮廓的对称均匀运动。我们得出结论，在所研究的技术中，面积法最适合用于左心室壁运动异常的定量分析。
