Hildes J A, Wilt J C, Parker W L, Stackiw W, Delaat A
Can Med Assoc J. 1965 Nov 6;93(19):1015-8.
A study was undertaken to determine the etiological agents responsible for epidemics in a small and relatively isolated Arctic community.Three serological surveys were carried out over a four-year period employing complement fixation tests. Clinical information from the resident nurse was also available.The results indicated that of the two clinical epidemics of "influenza" which occurred during the period of study one was due to influenza virus type A; the other was unidentified. However, influenza virus type B affected approximately 30% of the population at some time during a two-year period without being clinically recognized. An epidemic affecting mainly children, which was clinically considered to be whooping cough, was probably caused by an adenovirus. A mumps epidemic with a high attack rate for all age groups which had occurred a few months prior to the first survey was confirmed. Sendai virus and psittacosis virus are probably endemic in this community.
开展了一项研究,以确定在一个相对孤立的北极小社区中引发流行病的病原体。在四年期间进行了三次血清学调查,采用补体结合试验。还可获取驻院护士的临床信息。结果表明,在研究期间发生的两起“流感”临床流行病中,一起是由甲型流感病毒引起的;另一起病因不明。然而,乙型流感病毒在两年内的某个时间感染了约30%的人群,但未被临床识别。一场主要影响儿童的流行病,临床诊断为百日咳,可能是由腺病毒引起的。证实了在第一次调查前几个月发生的一次腮腺炎流行病,所有年龄组的发病率都很高。仙台病毒和鹦鹉热病毒可能在这个社区中呈地方性流行。