Quinlan J J, Schaffner V D, Hiltz J E
Can Med Assoc J. 1966 Jan 15;94(3):121-5.
Bronchiolar carcinoma is a malignant tumour which apparently arises in a terminal bronchiole from which it spreads either by bronchial embolization or by lymphogenous and/or hematogenous dissemination. It is not a common neoplasm.Histologically, the tumour bears a striking resemblance to the disease of sheep, jagziekte, which is of virus etiology. A very common finding in reported cases is preexisting pulmonary fibrosis. At the Nova Scotia Sanatorium, Kentville, 80 cases of primary lung cancer have been encountered within the past 25 years. Six of these were bronchiolar carcinomas. Five patients had co-existing chronic pulmonary disease, bronchiectasis in one and tuberculosis in four. One patient died of a rapidly progressive bilateral lesion and five were explored. Lobectomy was done in all five, but in one for palliation only. Three patients are alive and well three, six and 14 years, respectively, after their operations.
细支气管癌是一种恶性肿瘤，显然起源于终末细支气管，可通过支气管栓塞或经淋巴和/或血行播散。它不是一种常见的肿瘤。从组织学上看，该肿瘤与绵羊的疾病——雅司病（由病毒病因引起）极为相似。在报告的病例中，一个非常常见的发现是存在先前的肺纤维化。在新斯科舍省肯特维尔疗养院，在过去25年里共遇到80例原发性肺癌病例。其中6例为细支气管癌。5例患者同时患有慢性肺部疾病，1例为支气管扩张，4例为肺结核。1例患者死于迅速进展的双侧病变，另外5例接受了探查。所有5例均行肺叶切除术，但其中1例仅为姑息性手术。3例患者术后分别在3年、6年和14年时存活且状况良好。
