West Douglas, Nicholson Andrew G, Colquhoun Ian, Pollock James
Department of Cardiothoracic Surgery, The Royal Hospital for Sick Children, Dalnair Street, Glasgow, UK.
Ann Thorac Surg. 2007 Feb;83(2):687-9. doi: 10.1016/j.athoracsur.2006.06.029.
Congenital cystic adenomatoid malformation (CCAM) of lung is a rare condition with the potential for malignant transformation. We report a patient who underwent lobectomy for a cystic lung lesion, which was found to be a type 1 CCAM associated with a mucinous bronchioloalveolar carcinoma. Retrospective review of a biopsy specimen from the same lobe excised during an ipsilateral empyema drainage 11 years previously showed similar foci of bronchioloalveolar carcinoma. The patient remains well 3 years after surgery. This case demonstrates the indolent nature of malignancies seen in association with type 1 CCAMs and also that complete excision, probably by lobectomy, is the treatment of choice to avoid recurrence.
先天性肺囊性腺瘤样畸形（CCAM）是一种罕见疾病，有恶变可能。我们报告1例因肺部囊性病变接受肺叶切除术的患者，该病变为1型CCAM，伴有黏液性细支气管肺泡癌。回顾性分析11年前同侧脓胸引流时切除的同一肺叶活检标本，可见类似的细支气管肺泡癌病灶。患者术后3年情况良好。该病例显示了与1型CCAM相关的恶性肿瘤的惰性本质，也表明可能通过肺叶切除术进行完整切除是避免复发的首选治疗方法。
