多瘤肿瘤抗原免疫荧光所需的热不稳定血清因子。
Heat-labile serum factor required for immunofluorescence of polyoma tumor antigens.
作者信息
Takemoto K K, Malmgren R A, Habel K
出版信息
Science. 1966 Sep 2;153(3740):1122-3. doi: 10.1126/science.153.3740.1122.
PMID:4288238
Abstract
The immunofluorescent demonstration of polyoma tumor antigens in tumor cells requires a heatlabile serum component. With unheated hamster tumor serum, specific fluorescence was observed in polyoma-transformed hamster, mouse, and rat tumor cells. Heated serum usually gave little or no reactivity; the activity of such heated serum could be restored simply by the addition of fresh normal unheated hamster serum.
摘要
在肿瘤细胞中对多瘤病毒肿瘤抗原进行免疫荧光显示需要一种热不稳定的血清成分。使用未加热的仓鼠肿瘤血清时，在多瘤病毒转化的仓鼠、小鼠和大鼠肿瘤细胞中观察到特异性荧光。加热后的血清通常反应很少或没有反应；这种加热后血清的活性只需加入新鲜的未加热正常仓鼠血清就能恢复。
Zotero 插件