Straub E
Fortschr Med. 1979 May 10;97(18):856-62.
A significant increase in arterial blood pressure is considerably less common in childhood (as compared with adults), and, to a larger degree, is high-grade. The mild forms more frequently reverse spontaneously, and severe cases are more often asymptomatic. It is of a secondary nature in a much larger percentage (preponderantly of renal, but also of vascular, adrenal or other demonstrable etiology), i.e., susceptible to causal therapy. The growing interest within pediatrics in problems of primary (essential) hypertension with regard to epidemiology, etiology, pathogenetics and prognosis (!), lends additional importance to the particular difficulties involved in reliable blood pressure measurement and control, and additionally, the question of a useful definition of the criteria for pathological blood pressure increases, which is relatively uncertain in children (moreover, the normal values are highly age-dependent). The symptomatology of arterial hypertension shows certain age-specific characteristics. In the secondary forms, the underlying disease is ofter far advanced at the moment of manifestation and, even more so, of completion of the diagnosis. Certain risk factors (obviously also relevant for the later years of life) related to primary hypertension, the incidence of which is still quite controversial, can already be detected in childhood (familial and hereditary factors).
与成年人相比,儿童期动脉血压显著升高的情况相当少见,而且在很大程度上是重度的。轻度形式更常自发逆转,严重病例往往无症状。在很大比例的情况下(主要是肾脏原因,但也有血管、肾上腺或其他可证实的病因),它具有继发性,即易于进行病因治疗。儿科领域对原发性(特发性)高血压在流行病学、病因学、发病机制和预后(!)方面问题的兴趣日益浓厚,这使得可靠的血压测量和控制所涉及的特殊困难以及病理性血压升高标准的有用定义问题变得更加重要,而在儿童中这一问题相对不确定(此外,正常值高度依赖年龄)。动脉高血压的症状表现出某些特定年龄的特征。在继发性形式中,潜在疾病在表现出来时往往已经进展到相当程度,在诊断完成时更是如此。与原发性高血压相关的某些危险因素(显然对晚年生活也很重要)在儿童期就已可检测到,其发病率仍颇具争议(家族和遗传因素)。