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[高胆红素血症;诊断与治疗方面]

[Hyperbilirubinemias; diagnostic and therapeutic aspects].

作者信息

Schenk J

出版信息

Fortschr Med. 1979 Feb 1;97(5):177-81.

PMID:428854
Abstract

In the newborn functional disturbances of bilirubin metabolism may be threatening for the life of affected infants. Apart from states with massive overproduction of bilirubin caused by hemolytic crisis functional hyperbilirubinemias in adults represent preponderant hereditary disorders (Gilbert's syndrome, Dubin-Johnson-syndrome, Rotor-syndrome), full compatible with normal life span. Affected subjects are considered as normal persons and should be advised to live a normal life, avoiding however all well-known exogenous factors which may exacerbate the disease. The important clinical and characteristic diagnostic criteria of the mentioned disorders of bilirubin matabolism as well as the possibilities of their symptomatic therapy are discussed.

摘要

新生儿胆红素代谢功能紊乱可能会威胁到患病婴儿的生命。除了由溶血危象导致胆红素大量生成的情况外,成人的功能性高胆红素血症主要是遗传性疾病(吉尔伯特综合征、杜宾-约翰逊综合征、罗托综合征),完全可以正常寿命。患病个体被视为正常人,应建议其正常生活,但要避免所有可能加重病情的已知外部因素。本文讨论了上述胆红素代谢紊乱的重要临床和特征性诊断标准以及对症治疗的可能性。

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[Hyperbilirubinemias; diagnostic and therapeutic aspects].[高胆红素血症;诊断与治疗方面]
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