Stiehl A
Fortschr Med. 1982 May 13;100(18):842-5.
Jaundice is often the first and sometimes the only symptom of liver disease. Besides in parenchymal liver disease jaundice is also observed in chronic non-haemolytic hyperbilirubinemias (Crigler-Najjar type I and II, Gilbert's syndrome) and in hereditary conjugated hyperbilirubinaemias (Dubin-Johnson- and Rotor-syndrome). A specific therapy is only available for Crigler-Najjar type II which is treated with phenobarbitone.
黄疸通常是肝病的首要症状,有时也是唯一症状。除实质性肝病外,慢性非溶血性高胆红素血症(克里格勒 - 纳贾尔I型和II型、吉尔伯特综合征)以及遗传性结合胆红素血症(杜宾 - 约翰逊综合征和罗特综合征)也会出现黄疸。只有克里格勒 - 纳贾尔II型有特效疗法,可用苯巴比妥治疗。