伪狂犬病病毒光复活作用的特性

Characteristics of the photoreactivation of pseudorabies virus.

作者信息

Pfefferkorn E R, Burge B W, Coady H M

出版信息

J Bacteriol. 1966 Oct;92(4):856-61. doi: 10.1128/jb.92.4.856-861.1966.

DOI:10.1128/jb.92.4.856-861.1966

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC276345/

Abstract

Pfefferkorn, E. R. (Harvard Medical School, Boston, Mass.), Boyce W. Burge, and Helen M. Coady. Characteristics of the photoreactivation of pseudorabies virus. J. Bacteriol. 92:856-861. 1966.-Pseudorabies virus, killed with ultraviolet light and then allowed to adsorb to chick embryo tissue culture cells, can be photoreactivated by light of longer wavelengths. The photoreactivable sector is approximately 0.5. Herpes simplex virus is equally photoreactivable. Photoreactivability is negligible during the first 20 min after adsorption and then rises to a maximum by 100 min. After this maximum is reached, photoreactivability decreases with increasing rate as the temperature of incubation is raised. Inhibition of protein synthesis immediately after absorption prevents the establishment of the photoreactivable state.

摘要

费弗科恩，E.R.（马萨诸塞州波士顿哈佛医学院），博伊斯·W.伯奇，海伦·M.科迪。伪狂犬病病毒光复活作用的特性。《细菌学杂志》92:856 - 861。1966年。——用紫外线灭活后再使其吸附于鸡胚组织培养细胞的伪狂犬病病毒，可被较长波长的光光复活。可光复活部分约为0.5。单纯疱疹病毒同样可光复活。吸附后最初20分钟内光复活能力可忽略不计，然后在100分钟时升至最大值。达到此最大值后，随着培养温度升高，光复活能力以递增速率下降。吸附后立即抑制蛋白质合成可阻止光复活状态的建立。

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J Virol. 1972 Mar;9(3):474-8. doi: 10.1128/JVI.9.3.474-478.1972.

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Radiat Res. 1965 Apr;24:667-72.

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Science. 1964 Dec 11;146(3650):1474-6. doi: 10.1126/science.146.3650.1474.

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THE INTRACELLULAR FATE OF RABBITPOX VIRUS RENDERED NONINFECTIOUS BY VARIOUS REAGENTS.经各种试剂处理后失去感染性的兔痘病毒在细胞内的命运

Virology. 1964 Apr;22:620-33. doi: 10.1016/0042-6822(64)90084-4.

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Proc Natl Acad Sci U S A. 1964 Feb;51(2):293-300. doi: 10.1073/pnas.51.2.293.

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