伪狂犬病病毒光激活机制。
Mechanism of photeractivation of pseudorabies virus.
作者信息
Pfefferkorn E R, Coady H M
出版信息
J Virol. 1968 May;2(5):474-9. doi: 10.1128/JVI.2.5.474-479.1968.
Abstract
Primary chick embryo cultures were able to photoreactivate ultraviolet-treated pseudorabies virus. Upon exposure to fluorescent light, infected or uninfected chick cells eliminated thymine dimers induced in their deoxyribonucleic acid by ultraviolet irradiation. In contrast, rabbit kidney cells did not photoreactivate the virus or eliminate thymine dimers. Thus, the capacity for photoreactivation appeared to be determined by the ability of the cell to eliminate thymine dimers.
摘要
原代鸡胚培养物能够对紫外线处理过的伪狂犬病病毒进行光复活。暴露于荧光下时，感染或未感染的鸡细胞能够消除紫外线照射在其脱氧核糖核酸中诱导形成的胸腺嘧啶二聚体。相比之下，兔肾细胞既不能使病毒光复活，也不能消除胸腺嘧啶二聚体。因此，光复活能力似乎由细胞消除胸腺嘧啶二聚体的能力所决定。
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