正常人和结石患者的尿焦磷酸盐
Urinary pyrophosphate in normal subjects and in stone formers.
作者信息
O'Brien M M, Uhlemann I, McIntosh H W
出版信息
Can Med Assoc J. 1967 Jan 14;96(2):100-3.
The urinary excretion of inorganic pyrophosphate was determined in nine normal subjects and also in eight patients with recurrent calcium-containing renal stones during varied levels of phosphate intake. The excretion of pyrophosphate and orthophosphate is virtually the same in the two groups at all levels of phosphate intake. It appears unlikely that a consistently reduced urinary excretion of pyrophosphate is a factor in the formation of urinary calculi. Pyrophosphate excretion rose and calcium excretion fell with increasing phosphate intake; this might be expected to have a beneficial effect in patients with recurrent calcium stones.
在不同磷酸盐摄入量水平下，测定了9名正常受试者以及8名复发性含钙肾结石患者的无机焦磷酸盐尿排泄量。在所有磷酸盐摄入水平下，两组的焦磷酸盐和正磷酸盐排泄量实际上是相同的。持续降低的焦磷酸盐尿排泄量似乎不太可能是尿路结石形成的一个因素。随着磷酸盐摄入量增加，焦磷酸盐排泄量上升而钙排泄量下降；这可能对复发性含钙结石患者有有益影响。
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