Suen K C, Burton J D
Hum Pathol. 1979 Jan;10(1):31-43. doi: 10.1016/s0046-8177(79)80070-2.
Six cases of eosinophilic infiltration of the gastrointestinal tract were studied. Three cases were of the diffuse infiltrative variety (eosinophilic enteritis, two cases; eosinophilic peritonitis, one case), and three cases were of the circumscribed variety (so-called inflammatory fibroid polyp). Two of the infiltrative lesions showed necrotizing granulomas identical to those described by Churg and Strauss; one of the two also showed active vasculitis. One circumscribed lesion occurred in a patient with polyarteritis nodosa. Necrotizing eosinophilic granulomas were also noted in this lesion. Our observations suggest that the two forms of eosinophilic infiltration of the gastrointestinal tract are parts of a disease spectrum. Supporting evidence in the literature is presented. The relationship of this group of eosinophilic lesions to the hypereosinophilic syndrome, allergic granulomatosis and angiitis of Churg and Strauss, and polyarteritis nodosa is discussed.
对6例胃肠道嗜酸性粒细胞浸润病例进行了研究。3例为弥漫浸润型（嗜酸性肠炎2例；嗜酸性腹膜炎1例），3例为局限性型（所谓的炎性纤维瘤性息肉）。2例浸润性病变显示出与Churg和Strauss所描述的相同的坏死性肉芽肿；其中1例还显示出活动性血管炎。1例局限性病变发生在一名结节性多动脉炎患者中。该病变中也发现了坏死性嗜酸性肉芽肿。我们的观察结果表明，胃肠道嗜酸性粒细胞浸润的两种形式是疾病谱的一部分。文中提供了文献中的支持证据。讨论了这组嗜酸性粒细胞病变与高嗜酸性粒细胞综合征、Churg和Strauss的过敏性肉芽肿病和血管炎以及结节性多动脉炎的关系。
