Fischer C P, Sonda L P
Invest Urol. 1979 Jan;16(4):266-9.
A fibrin clot forming an extractable cast or "coagulum" of the pyelocalyceal system was developed and characterized using a blood product not previously described--single donor type specific cryoprecipitate. The physical properties of the cryoprecipitate coagulum were investigated and compared with other described formulations. Simulated coagulum pyelolithotomy was performed in vivo in 11 canine kidneys with no adverse effect upon creatinine clearance or anatomic integrity. The advantages of the cryoprecipitate are detailed and a new, simplified operative technique is described.
使用一种此前未描述过的血液制品——单供体特异性冷沉淀，形成了肾盂肾盏系统的可提取铸型或“凝块”纤维蛋白凝块，并对其进行了表征。研究了冷沉淀凝块的物理特性，并与其他已描述的制剂进行了比较。在11只犬肾中进行了体内模拟凝块肾盂切开取石术，对肌酐清除率或解剖完整性均无不良影响。详细介绍了冷沉淀的优点，并描述了一种新的、简化的手术技术。
