Resnick M I, Boyce W H
Invest Urol. 1979 Jan;16(4):270-3.
Twenty-four hour urine specimens were obtained from 20 active calcium oxalate stone formers, 20 inactive calcium oxalate stone formers, 8 struvite stone formers, and 9 non-stone forming controls. Proteins with molecular weights less than 50,000 daltons were concentrated by ultrafiltration and separated by sodium dodecyl sulfate polyacrylamide gel electrophoresis. Fourteen of the 17 active calcium oxalate stone formers had low molecular weight urinary proteins (less than 35,000 daltons) present in their urine whereas none of the inactive stone formers or struvite stone formers had similar patterns. Only one of the nine control patients had similar proteins present.
从20名活动性草酸钙结石形成者、20名非活动性草酸钙结石形成者、8名磷酸铵镁结石形成者和9名无结石形成的对照者中获取24小时尿液标本。分子量小于50,000道尔顿的蛋白质通过超滤浓缩，并通过十二烷基硫酸钠聚丙烯酰胺凝胶电泳进行分离。17名活动性草酸钙结石形成者中有14名尿液中存在低分子量尿蛋白（小于35,000道尔顿），而非活动性结石形成者或磷酸铵镁结石形成者均无类似情况。9名对照患者中只有1名存在类似蛋白质。
