痘苗病毒DNA复制过程中交联分子的形成。

Formation of cross-linked molecules during vaccinia DNA replication.

作者信息

Pogo B G

出版信息

Intervirology. 1979;11(3):196-200. doi: 10.1159/000149034.

Abstract

The appearance of cross-linked DNA molecules during the replication of vaccinia virus DNA was investigated. Conversion of full size DNA molecules to cross-linked molecules occurs several hours after completion of DNA synthesis. Inhibition of RNA synthesis by actinomycin D did not prevent this transition; however, interruption of protein synthesis by streptovitacin A resulted in partial inhibition of the process.

摘要

对痘苗病毒DNA复制过程中交联DNA分子的出现进行了研究。全尺寸DNA分子向交联分子的转变发生在DNA合成完成后的数小时。放线菌素D对RNA合成的抑制并未阻止这种转变；然而，链黑菌素A对蛋白质合成的阻断导致该过程受到部分抑制。