δ-7-胆甾烯-3-β-醇酶促转化为7-脱氢胆固醇过程中的立体特异性 - Suppr

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Stereospecificity in the enzymatic conversion of delta-7-cholesten-3-beta-ol to 7-dehydrocholesterol.

作者信息

Paliokas A M, Schroepfer G J

出版信息

J Biol Chem. 1968 Feb 10;243(3):453-64.

PMID:4295374

Abstract

摘要

相似文献

Stereospecificity in the enzymatic conversion of delta-7-cholesten-3-beta-ol to 7-dehydrocholesterol.δ-7-胆甾烯-3-β-醇酶促转化为7-脱氢胆固醇过程中的立体特异性

J Biol Chem. 1968 Feb 10;243(3):453-64.

Enzymatic stereospecificity in the conversion of delta-7-cholesten-3-beta-ol to 7-dehydrocholesterol.

Biochem Biophys Res Commun. 1967 Mar 21;26(6):736-41. doi: 10.1016/s0006-291x(67)80135-9.

Studies on the mechanism of the enzymatic conversion of delta 8-cholesten-3 beta-ol to delta 7-cholesten-3 beta-ol.关于δ8-胆甾烯-3β-醇酶促转化为δ7-胆甾烯-3β-醇机制的研究。

J Biol Chem. 1969 Apr 25;244(8):2033-40.

The conversion of cholesterol to delta-5,7,22-cholestatrien-3-beta-ol by Tetrahymena pyriformis.嗜热四膜虫将胆固醇转化为Δ⁵,⁷,²²-胆甾三烯-3-β-醇。

J Biol Chem. 1969 May 10;244(9):2325-33.

Squalene-2,3oxide, an intermediate in the enzymatic conversion of squalene to lanosterol and cholesterol.角鲨烯-2,3-氧化物，是角鲨烯酶促转化为羊毛甾醇和胆固醇过程中的一种中间体。

J Biol Chem. 1967 Sep 25;242(18):4182-91.

Biosynthesis of delta-7-cholesten-3-beta-ol, delta-5,7-cholestadien-3-beta-ol, and delta-5-cholesten-3-beta-ol by guinea pig intestinal mucosa in vitro.豚鼠肠黏膜体外合成Δ-7-胆甾烯-3-β-醇、Δ-5,7-胆甾二烯-3-β-醇和Δ-5-胆甾烯-3-β-醇。

J Lipid Res. 1966 Nov;7(6):750-7.

Enzymatic conversion of delta8, 14-cholestadien-3beta-ol to cholesterol.将δ8,14-胆甾二烯-3β-醇酶促转化为胆固醇。

Biochem Biophys Res Commun. 1968 Nov 8;33(3):492-6. doi: 10.1016/0006-291x(68)90602-5.

The stereospecificity of the cholesterol delta 22-dehydrogenase of Tetrahymena pyriformis and the origin of the C-22 protons of cholesterol.梨形四膜虫胆固醇δ22 -脱氢酶的立体特异性及胆固醇C - 22质子的来源

J Biol Chem. 1970 Apr 10;245(7):1682-7.

Enzymatic conversion of 14-alpha-methyl-cholest-7-en-3 beta, 15 zeta-diol to cholesterol.

Biochem Biophys Res Commun. 1970;39(6):1170-4. doi: 10.1016/0006-291x(70)90683-2.

Concerning the role of lanosterol and cycloartenol in steroid biosynthesis.关于羊毛甾醇和环阿屯醇在类固醇生物合成中的作用。

J Biol Chem. 1971 Jun 25;246(12):3967-76.

引用本文的文献

The stereochemistry of hydrogen elimination during 7,8-double bond formation by Tetrahymena pyriformis.梨形四膜虫在形成7,8-双键过程中氢消除的立体化学

Biochem J. 1970 Feb;116(3):337-9. doi: 10.1042/bj1160337.

The stereochemistry of hydrogen elimination at C-7,C-22 and C-23 during the conversion of cholesterol (cholest-5-en-3 beta-ol) into cholesta-5,7,22-trien-3 beta-ol by Tetrahymena pyriformis.嗜热四膜虫将胆固醇（胆甾-5-烯-3β-醇）转化为胆甾-5,7,22-三烯-3β-醇过程中，C-7、C-22和C-23处氢消除的立体化学。

Biochem J. 1969 Dec;115(4):857-8. doi: 10.1042/bj1150857.

Incorporation of (2-14C, (5r)-5-3H1) mevalonic acid into cholesterol by a rat liver homogenate and into beta-sitosterol and 28-isofucosterol by larix decidua leaves.大鼠肝脏匀浆将（2-¹⁴C，（5r）-5-³H¹）甲羟戊酸掺入胆固醇中，落叶松叶片将其掺入β-谷甾醇和28-异岩藻甾醇中。

Biochem J. 1969 Oct;114(4):885-92. doi: 10.1042/bj1140885.

Enzymatic conversion of 5alpha-cholest-8(14)-en-3beta-o1 to 5alpha-cholesta-8,14-dien-3beta-o1.将5α-胆甾-8(14)-烯-3β-醇酶促转化为5α-胆甾-8,14-二烯-3β-醇。

Lipids. 1971 Dec;6(12):957-9. doi: 10.1007/BF02531180.

Oleate hydratase: studies of substrate specificity.油酸水合酶：底物特异性研究

Lipids. 1971 Aug;6(8):541-5. doi: 10.1007/BF02531133.

The effect of carbon monoxide on the nature of the accumulated 4,4-dimethyl sterol precursors of cholesterol during its biosynthesis from (2-14C)mevalonic acid in vitro.一氧化碳对体外由（2-¹⁴C）甲羟戊酸生物合成胆固醇过程中积累的4,4-二甲基甾醇前体性质的影响。

Biochem J. 1973 Mar;132(3):439-48. doi: 10.1042/bj1320439.

Biosynthesis of carotenoids and plant triterpenes.类胡萝卜素与植物三萜类化合物的生物合成

Biochem J. 1971 Jul;123(3):293-329. doi: 10.1042/bj1230293.

Enzymatic conversion of 5alpha-cholesta-7, 14-dien-3beta-ol to 5alpha-cholesta-8, 14-dien-3beta-ol.5α-胆甾-7,14-二烯-3β-醇向5α-胆甾-8,14-二烯-3β-醇的酶促转化。

Lipids. 1975 Oct;10(10):623-6. doi: 10.1007/BF02532727.

The role of a 5alpha-hydroxylated intermediate in the formation of the 5, 6-double bond in cholesterol biosynthesis.5α-羟基化中间体在胆固醇生物合成中5,6-双键形成过程中的作用。

Biochem J. 1975 Feb;145(2):345-52. doi: 10.1042/bj1450345.

Inhibition of enzymatic reduction of delta 14-double bond of 5 alpha-cholesta-8,14-dien-3 beta-ol and 5 alpha-cholesta-7,14-dien-3 beta-ol by AY-9944.AY-9944对5α-胆甾-8,14-二烯-3β-醇和5α-胆甾-7,14-二烯-3β-醇δ14-双键酶促还原反应的抑制作用

Lipids. 1975 Jan;10(1):9-11. doi: 10.1007/BF02532186.

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