Brown O R, Silverberg R G, Huggett D O
Appl Microbiol. 1968 Feb;16(2):260-2. doi: 10.1128/am.16.2.260-262.1968.
Three strains of Pseudomonas aeruginosa were directly exposed on the surface of membrane filters to hyperoxic atmospheres. One of the three strains was found to be sensitive to oxygen. Colonies failed to appear during 18 hr of incubation in pure oxygen at 1 atm, but about 40% of the bacteria recovered to produce colonies upon reincubation in air. Similar killing was produced by 10 hr of oxygen exposure. No inhibition or killing was observed with two other strains. Streptomycin (1mug/ml) and kanamycin (5mug/ml) were more effective in killing the oxygen-sensitive strain in the presence of 60 to 70% oxygen than in air, but polymyxin B (5mug/ml) did not show a synergistic effect under such conditions.
将三株铜绿假单胞菌直接暴露于滤膜表面的高氧环境中。发现三株菌中有一株对氧气敏感。在1个标准大气压的纯氧环境中培养18小时期间未出现菌落，但在空气中重新培养时，约40%的细菌恢复生长并形成菌落。暴露于氧气10小时也产生了类似的杀菌效果。另外两株菌未观察到抑制或杀灭现象。在60%至70%氧气存在的情况下，链霉素（1微克/毫升）和卡那霉素（5微克/毫升）比在空气中更有效地杀灭对氧气敏感的菌株，但多粘菌素B（5微克/毫升）在这种条件下未显示协同作用。
