用聚合豚草抗原治疗的豚草花粉热患者的免疫反应。

The immune response of patients with ragweed hay fever treated with polymerized ragweed antigens.

作者信息

Zeiss C R, Ungs C J, Levitz D, Suszko I M, Patterson R

出版信息

J Allergy Clin Immunol. 1979 Apr;63(4):273-5. doi: 10.1016/0091-6749(79)90112-x.

Abstract

This report describes the immune response of patients with ragweed hay fever treated with polymerized ragweed antigens (PRW). Their IgG antibody responses to crude ragweed extract, antigen E, antigen K, and antigen Ra3 were determined by a solid-phase radioimmunoassay. The results indicate that PRW contains an array of clinically important antigens that are available for immunologic processing and result in an immune response in patients treated with this new form of immunotherapy for ragweed hay fever.

摘要

本报告描述了用聚合豚草抗原（PRW）治疗的豚草花粉热患者的免疫反应。通过固相放射免疫测定法测定了他们对粗豚草提取物、抗原E、抗原K和抗原Ra3的IgG抗体反应。结果表明，PRW含有一系列临床上重要的抗原，这些抗原可用于免疫加工，并在用这种新型免疫疗法治疗豚草花粉热的患者中引发免疫反应。