皮肤癣菌产生抗生素的生态效应。
Ecological effects of antibiotic production by dermatophyte fungi.
作者信息
Youssef N, Wyborn C H, Holt G, Noble W C, Clayton Y M
出版信息
J Hyg (Lond). 1979 Apr;82(2):301-7. doi: 10.1017/s0022172400025717.
Abstract
Antibiotic production by dermatophyte fungi has been demonstrated in vivo in the lesions of patients with dermatomycoses. Patients infected with antibiotic-producing strains more frequently carried cocci resistant to penicillin and other antibiotics than did patients infected with non-producer strains. The total bacterial load was less in lesions caused by producer fungi. In vitro studies demonstrated the selection of penicillin-resistant S. aureus from mixed populations of resistant and sensitive cells.
摘要
皮肤癣菌在皮肤真菌病患者的皮损中可在体内产生抗生素。与感染非产抗生素菌株的患者相比，感染产抗生素菌株的患者更频繁地携带对青霉素和其他抗生素耐药的球菌。产抗生素真菌引起的皮损中细菌总数较少。体外研究表明，从耐药和敏感细胞的混合群体中可筛选出耐青霉素的金黄色葡萄球菌。
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