急性坏死性麻风性淋巴结炎：一种淋巴结内的结节性红斑样麻风反应。
Acute necrotizing lepromatous lymphadenitis: an erythema-nodosum-leprosum-like reaction in lymph nodes.
作者信息
Karat A B, Karat S, Job C K, Sudarsanam D
出版信息
Br Med J. 1968 Oct 26;4(5625):223-4. doi: 10.1136/bmj.4.5625.223.
Histological examination of lymph-node biopsy specimens in 12 patients with erythema nodosum leprosum showed almost complete replacement of the node by lepromatous granuloma, together with considerable polymorph infiltration. Ziehl-Neelsen staining demonstrated numerous Mycobacterium leprae present in the nodes. The majority of these patients were very ill, and responded to prednisolone or corticotrophin.It is suggested that the histological appearances may represent an intensive inflammatory response in the lymph nodes followed by avascular aseptic necrosis.
对12例瘤型麻风结节性红斑患者的淋巴结活检标本进行组织学检查，结果显示淋巴结几乎完全被瘤型肉芽肿取代，同时伴有大量多形核细胞浸润。齐-尼氏染色显示淋巴结中有大量麻风杆菌。这些患者大多数病情严重，对泼尼松龙或促肾上腺皮质激素有反应。有人认为，组织学表现可能代表淋巴结内强烈的炎症反应，随后出现无血管性无菌性坏死。
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