Soloviev V D, Krispin T I, Zaslavsky V G, Agol V I
J Virol. 1968 Jun;2(6):553-7. doi: 10.1128/JVI.2.6.553-557.1968.
Two cell lines, M10-45-2 and L-41, were studied, each of which possessed specific resistance either to poliovirus or to coxsackievirus. Infection of M10-45-2 cells with poliovirus ribonucleic acid (RNA) and L-41 cells with infectious coxsackievirus RNA was accompanied by production of complete viruses in each of the resistant cell lines. During incubation of the cells with the virus to which they were resistant, the amount of infectious virus did not decrease. Treatment with glycine-HCl buffer solution (pH 2.5) of resistant M10-45-2 cells after incubation with poliovirus at 0 C did not result in recovery of infectious virus, although such release did take place after treatment of sensitive M10 cells. Infection of resistant cells with virus containing poliovirus RNA and coxsackievirus proteins resulted in production of poliovirus in M10-45-2 cells but not in L-41 cells. The resistant cells are apparently unable to adsorb the virus to which they are resistant.
对两种细胞系M10 - 45 - 2和L - 41进行了研究，每种细胞系对脊髓灰质炎病毒或柯萨奇病毒都具有特异性抗性。用脊髓灰质炎病毒核糖核酸（RNA）感染M10 - 45 - 2细胞，并用感染性柯萨奇病毒RNA感染L - 41细胞，在每种抗性细胞系中都伴随着完整病毒的产生。在用它们具有抗性的病毒培养细胞的过程中，感染性病毒的量没有减少。在0℃下用脊髓灰质炎病毒培养抗性M10 - 45 - 2细胞后，用甘氨酸 - 盐酸缓冲溶液（pH 2.5）处理，并未使感染性病毒恢复，尽管在用敏感的M10细胞处理后确实发生了这种释放。用含有脊髓灰质炎病毒RNA和柯萨奇病毒蛋白的病毒感染抗性细胞，导致M10 - 45 - 2细胞中产生脊髓灰质炎病毒，但L - 41细胞中未产生。抗性细胞显然无法吸附它们具有抗性的病毒。
