Larkin E P, Fassolitis A C
Appl Environ Microbiol. 1979 Oct;38(4):650-5. doi: 10.1128/aem.38.4.650-655.1979.
High-titer suspensions of poliovirus 1 and coxsackievirus B-2 were shown to contain a heat-resistant fraction when heated for 65 min at temperature ranging from 56 to 70 degrees C. The addition of ribonuclease to the heated suspensions eliminated plaque production in the cell cultures, indicating that the resistant fraction was infectious ribonucleic acid that had been liberated from ruptured viruses during the heating process.
脊髓灰质炎病毒1型和柯萨奇病毒B - 2的高滴度悬液在56至70摄氏度的温度下加热65分钟后,显示含有耐热部分。向加热后的悬液中加入核糖核酸酶可消除细胞培养中的蚀斑形成,这表明抗性部分是在加热过程中从破裂病毒中释放出来的传染性核糖核酸。