Ide P R, Thomson R G, Ditchfield W J
Can J Comp Med. 1969 Jan;33(1):1-9.
Twenty-four dairy calves ranging in age from six to 15 weeks were divided so that 10 were inoculated with bovine adenovirus serotype 1 (BA-1), eight were inoculated with bovine adenovirus serotype 3 (BA-3), and six were inoculated with control tissue culture and fluids.Post-inoculation serum samples from most of the calves presented evidence of adenovirus infection, but none of the animals exhibited signs of respiratory or enteric disease. Histopathological examination of lung tissue was not considered to be specific for adenovirus pneumonia, but was characterized by peribronchial cuffing and slight aspiration pneumonia. BA-1 was not isolated from any of the inoculated calves, and BA-3 was only recovered from the feces of two animals. Reasons for the discrepancy between these results and those of other workers are considered, and the etiology of peribronchial cuffing is briefly discussed.
24头年龄在6至15周的奶牛犊被分成三组，其中10头接种1型牛腺病毒（BA-1），8头接种3型牛腺病毒（BA-3），6头接种对照组织培养物和液体。大多数犊牛接种后的血清样本显示出腺病毒感染的迹象，但没有动物表现出呼吸道或肠道疾病的症状。肺组织的组织病理学检查不被认为是腺病毒肺炎的特异性表现，其特征为支气管周围套袖状浸润和轻度吸入性肺炎。在任何接种的犊牛中均未分离到BA-1，仅从两只动物的粪便中分离到BA-3。文中考虑了这些结果与其他研究者结果存在差异的原因，并简要讨论了支气管周围套袖状浸润的病因。
