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儿童先天性畸形与胚胎肿瘤的巧合。

Coincidence of congenital malformation and embryonic tumours of childhood.

作者信息

Berry C L, Keeling J, Hilton C

出版信息

Arch Dis Child. 1970 Apr;45(240):229-31. doi: 10.1136/adc.45.240.229.

Abstract

Examination of the records of cases of neuroblastoma, nephroblastoma, hepatoblastoma, and teratoma has not revealed a significant association between neoplasia and malformation. An increase in 'local' abnormalities in sacrococcygeal teratomata might be explained by local growth effects. The significance of the definition of malformation, the validity of comparisons between 'general incidence' figures for malformations, and those obtained in tumour-bearing patients is considered.

摘要

对神经母细胞瘤、肾母细胞瘤、肝母细胞瘤和畸胎瘤病例记录的检查未发现肿瘤形成与畸形之间存在显著关联。骶尾部畸胎瘤中“局部”异常的增加可能由局部生长效应来解释。文中考虑了畸形定义的重要性、畸形“总体发生率”数据与肿瘤患者中所获数据之间比较的有效性。

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