Zaidi S H, Kaw J L
Br J Ind Med. 1970 Jul;27(3):250-9. doi: 10.1136/oem.27.3.250.
250-259. In order to determine whether the dietary deficiency, which may occur in miners in India, is likely to influence their response to silica dust, two experiments were carried out on rats. In both experiments rats were exposed to silica dust by intratracheal inoculation of saline suspension, the dose being sufficient to cause marked fibrosis in normal rats. In the first experiment rats were fed on a multiple deficient diet and in the second on a diet grossly deficient in protein but otherwise adequate. Although these diets caused other evidence of dietary deficiency, in neither group was there any difference in the extent of silicotic fibrosis as assessed by histological or biochemical methods.
250 - 259。为了确定印度矿工中可能出现的饮食缺乏是否可能影响他们对二氧化硅粉尘的反应，对大鼠进行了两项实验。在两项实验中，通过气管内接种盐水悬浮液使大鼠接触二氧化硅粉尘，该剂量足以在正常大鼠中引起明显的纤维化。在第一个实验中，给大鼠喂食多种缺乏的饮食，在第二个实验中，给大鼠喂食蛋白质严重缺乏但其他方面充足的饮食。尽管这些饮食导致了饮食缺乏的其他证据，但通过组织学或生化方法评估，两组的矽肺纤维化程度均无差异。
