三甲氧苯乙胺引起的大脑皮质核糖体变化。三甲氧苯乙胺对大脑皮质核糖体稳定性的影响。
Mescaline-induced changes of brain-cortex ribosomes. Effect of mescaline on the stability of brain-cortex ribosomes.
作者信息
Datta R K, Ghosh J J
出版信息
Biochem J. 1970 May;117(5):961-8. doi: 10.1042/bj1170961.
Abstract
- During the action of mescaline sulphate on goat brain-cortex slices the ribosomal particles become susceptible to breakdown, releasing protein, RNA, acidsoluble nucleotides and ninhydrin-positive materials, resulting in loss of ribosomal enzyme activities. 2. Ribosomes of the mescaline-treated cortex slices undergo rapid degradation in the presence of trypsin and ribonuclease. 3. Mescaline does not alter the chemical and nucleotide compositions or the u.v.-absorption characteristics of ribosomal particles, however.
摘要
- 在硫酸三甲氧苯乙胺作用于山羊脑皮层切片的过程中，核糖体颗粒变得易于分解，释放出蛋白质、RNA、酸溶性核苷酸和茚三酮阳性物质，导致核糖体酶活性丧失。2. 在胰蛋白酶和核糖核酸酶存在的情况下，经三甲氧苯乙胺处理的皮层切片中的核糖体迅速降解。3. 然而，三甲氧苯乙胺不会改变核糖体颗粒的化学组成、核苷酸组成或紫外吸收特性。
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引用本文的文献
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Mescaline-induced changes of brain-cortex ribosomes. Effect of mescaline on the hydrogen-bonded structure of ribonucleic acid of brain-cortex ribosomes.麦司卡林引起的大脑皮质核糖体变化。麦司卡林对大脑皮质核糖体核糖核酸氢键结构的影响。
Biochem J. 1970 May;117(5):969-80. doi: 10.1042/bj1170969.
2
Mescaline-induced changes of brain-cortex ribosomes. Role of sperimidine in counteracting the destabilizing effect of mescaline of brain-cortex ribosomes.三甲氧苯乙胺引起的大脑皮质核糖体变化。精脒在对抗三甲氧苯乙胺对大脑皮质核糖体的去稳定作用中的作用。
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3
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ACTION OF ISONIAZID AND NIALAMIDE ON BRAIN CORTEX RIBOSOMES.异烟肼和尼亚酰胺对大脑皮质核糖体的作用。
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