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小儿应用锝-99m-酸性N-(2,6-二乙基乙酰苯胺)亚氨基二乙酸进行胆管闪烁扫描术

[Scintigraphy of the bile ducts by means of the Tc-99m-acid N-(2,6 diethyl-acetanilide) iminodiacetic acid in pediatrics].

作者信息

Mussa G C, Bona G, Silvestro L

出版信息

Minerva Med. 1979 Jan 28;70(4):307-16.

PMID:431860
Abstract

Results with diethyl-IDA in the diagnosis of dilatation and obstruction of the bile ducts are reported. By comparison with methyl-IDA, the more rapid blood clearance and slower renal excretion of diethyl-IDA do not lead to interference on the part of the right kidney and ureter during the first 30' of scintiscanning. The preparation was employed in 15 subjects with persistent neonatal icterus and clinically suspected diseases of the hepatic bile ducts. Personal experience is cited for the view that, thanks to its almost exclusively biliary excretion and high bile concentration, 99mTc-labelled diethyl-IDA gives better visualisation of the bile ducts than the methyl-IDA complex.

摘要

本文报告了二乙基亚氨基二乙酸(diethyl-IDA)在胆管扩张和梗阻诊断中的应用结果。与甲基亚氨基二乙酸(methyl-IDA)相比,二乙基亚氨基二乙酸更快的血液清除率和更慢的肾脏排泄率,使得在闪烁扫描的前30分钟内右肾和输尿管不会产生干扰。该制剂用于15例持续性新生儿黄疸且临床怀疑有肝内胆管疾病的患者。文中引用个人经验表明,由于99mTc标记的二乙基亚氨基二乙酸几乎完全经胆汁排泄且胆汁浓度高,因此比甲基亚氨基二乙酸复合物能更好地显示胆管。

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