猫对吗啡及某些相关物质诱导的药物低敏反应
Hyposensitivity to drugs induced by morphine and some related substances in the cat.
作者信息
Contreras E, Huidobro F
出版信息
Br J Pharmacol. 1970 Aug;39(4):789-97. doi: 10.1111/j.1476-5381.1970.tb09905.x.
Abstract
- Hyposensitivity to noradrenaline occurred concomitantly with morphine tachyphylaxis in the absence of any obvious depressant effect on the heart or peripheral circulation.2. The actions of adrenaline, noradrenaline and angiotensin and, occasionally, other drugs were tested before and after repeated injections of morphine or one of ten related substances in various preparations of the spinal cat.3. Tachyphylaxis in response to morphine could be related to a simultaneous decrease in the tissue responses to adrenaline, noradrenaline and angiotensin but such a parallelism has not been shown for the substances related to morphine.
摘要
- 在对心脏或外周循环无任何明显抑制作用的情况下，去甲肾上腺素低敏反应与吗啡快速耐受同时出现。2. 在脊髓猫的各种制剂中，在重复注射吗啡或十种相关物质之一之前和之后，测试了肾上腺素、去甲肾上腺素和血管紧张素以及偶尔其他药物的作用。3. 对吗啡的快速耐受可能与组织对肾上腺素、去甲肾上腺素和血管紧张素的反应同时降低有关，但尚未表明与吗啡相关的物质存在这种平行关系。
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Cardiovascular effects of morphine, pethidine, diamorphine and nalorphine on the cat and rabbit.吗啡、哌替啶、二醋吗啡和烯丙吗啡对猫和兔的心血管作用。
Br J Pharmacol. 1971 Jun;42(2):159-78. doi: 10.1111/j.1476-5381.1971.tb07098.x.
本文引用的文献
1
THE INHIBITION OF AUTONOMIC NEURO-EFFECTOR TRANSMISSION BY MORPHINE-LIKE DRUGS AND ITS USE AS A SCREENING TEST FOR NARCOTIC ANALGESIC DRUGS .吗啡类药物对自主神经效应器传递的抑制作用及其作为麻醉性镇痛药筛选试验的应用。
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1964 May 25;248:231-46. doi: 10.1007/BF00348594.
2
Studies on cellular adaptation to morphine and its reversal by nalorphine in cerebral cortical slices of rats.大鼠大脑皮层切片中细胞对吗啡的适应性及其经烯丙吗啡逆转的研究。
J Pharmacol Exp Ther. 1962 Jan;135:89-93.
3
Effect of morphine on some sympathetically innervated effectors.吗啡对某些受交感神经支配的效应器的作用。
Br J Pharmacol Chemother. 1961 Dec;17(3):539-51. doi: 10.1111/j.1476-5381.1961.tb01141.x.
4
The effect of morphine on vagal inhibition of the heart.吗啡对迷走神经抑制心脏的作用。
Br J Pharmacol Chemother. 1959 Jun;14(2):209-14. doi: 10.1111/j.1476-5381.1959.tb01385.x.
5
The inhibitory action of morphine on the contraction of the longitudinal muscle coat of the isolated guinea-pig ileum.吗啡对离体豚鼠回肠纵行肌层收缩的抑制作用。
Br J Pharmacol Chemother. 1958 Sep;13(3):296-303. doi: 10.1111/j.1476-5381.1958.tb00906.x.
6
The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum.吗啡及相关物质对同轴刺激的豚鼠回肠收缩和乙酰胆碱释放的作用。
Br J Pharmacol Chemother. 1957 Mar;12(1):119-27. doi: 10.1111/j.1476-5381.1957.tb01373.x.
7
Inhibition by morphine of the release of acetylcholine from the intestine of the guinea-pig.吗啡对豚鼠肠道乙酰胆碱释放的抑制作用。
Br J Pharmacol Chemother. 1957 Mar;12(1):115-8. doi: 10.1111/j.1476-5381.1957.tb01372.x.
8
The action of morphine on the superior cervical ganglion and on the nictitating membrane of the cat.吗啡对猫颈上神经节及瞬膜的作用。
Br J Pharmacol Chemother. 1957 Mar;12(1):79-85. doi: 10.1111/j.1476-5381.1957.tb01366.x.
9
Effect of aromatic amines on neuromuscular function.芳香胺对神经肌肉功能的影响。
Acta Physiol Lat Am. 1952 Jul;2(2):107-18.
10
The fall of blood pressure caused by intravenous morphine in the rat and the cat.静脉注射吗啡对大鼠和猫血压的影响。 （注：原英文标题表述不太准确，这里根据内容理解进行了意译，更准确的翻译应该是“静脉注射吗啡导致大鼠和猫血压下降” ，但按指令要求，需按原文翻译为“静脉注射吗啡对大鼠和猫血压的影响” ）
Br J Pharmacol Chemother. 1952 Dec;7(4):542-52. doi: 10.1111/j.1476-5381.1952.tb00720.x.
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