狨猴中疱疹病毒绢毛猴携带状态的出现。
Occurrence of a carrier state for Herpesvirus tamarinus in Marmosets.
作者信息
Murphy B L, Maynard J E, Krushak D H, Fields R M
出版信息
Appl Microbiol. 1971 Jan;21(1):50-2. doi: 10.1128/am.21.1.50-52.1971.
The ecology of herpesviruses in marmosets and other nonhuman primates is important today, for colonies of these animals are being established for biomedical research. This paper presents the first reported isolations of Herpesvirus tamarinus from throat swabs of a healthy white-lipped marmoset carrier (Saguinus nigricollis) during a 2-month period. Infectivity studies with this virus in both white-moustached (S. mystax) and white-lipped marmosets demonstrated that the virus is not lethal to white-moustached marmosets (perhaps a more resistant species) at 1,000 TCID(50). Which environmental conditions trigger the unmasking of herpesviruses in marmosets is not known. Hoever, intermittent H. tamarinus shedding may help explain spontaneous infections in established colonies as well as suggest an additional mechanism for transmission of virus between marmosets under natural conditions.
如今，狨猴及其他非人灵长类动物中疱疹病毒的生态学研究十分重要，因为这些动物的群体正被建立用于生物医学研究。本文首次报道了在两个月的时间里，从一只健康的白唇狨猴携带者（黑颈柽柳猴）的咽喉拭子中分离出塔马林猴疱疹病毒。对该病毒在白须柽柳猴和白唇狨猴中的感染性研究表明，在1000个半数组织培养感染剂量（TCID50）时，该病毒对白须柽柳猴（可能是更具抵抗力的物种）并不致命。目前尚不清楚哪些环境条件会引发狨猴体内疱疹病毒的暴露。然而，塔马林猴疱疹病毒的间歇性脱落可能有助于解释已建立群体中的自发感染现象，也提示了在自然条件下该病毒在狨猴之间传播的另一种机制。
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