逆行性遗忘：快速眼动睡眠剥夺终止后的电休克效应。

Retrograde amnesia: electroconvulsive shock effects after termination of rapid eye movement sleep deprivation.

作者信息

Fishbein W, McGaugh J L, Swarz J R

出版信息

Science. 1971 Apr 2;172(3978):80-2. doi: 10.1126/science.172.3978.80.

DOI:10.1126/science.172.3978.80

Abstract

Mice that were deprived of rapid eye movement sleep for 2 days immediately after one-trial training in an inhibitory avoidance task and were given an electroconvulsive shock after deprivation displayed retrograde amnesia on a retention test given 24 hours later. Electroconvulsive shock produced no amnesia in comparable groups of animals that were not deprived of rapid eye movement sleep.

摘要

在抑制性回避任务中经过单次训练后立即被剥夺快速眼动睡眠2天的小鼠，在剥夺睡眠后给予电惊厥休克，在24小时后进行的记忆保持测试中表现出逆行性遗忘。电惊厥休克在未被剥夺快速眼动睡眠的可比动物组中未产生遗忘。