Sheppard J R, Levine A J, Burger M M
Science. 1971 Jun 25;172(3990):1345-6. doi: 10.1126/science.172.3990.1345.
The change in the surface structure of cultutred mammalian cells infected with oncogenic DNA viruses was similar to that described for the fully and permanently transformed cell surfaces. The course of appearance of this change was established. Synthesis of host DNA is required for expression of the surface change triggered by infection with the oncogenic virus.
感染致癌DNA病毒的培养哺乳动物细胞表面结构的变化与完全和永久转化的细胞表面所描述的变化相似。确定了这种变化出现的过程。致癌病毒感染引发的表面变化的表达需要宿主DNA的合成。