Lilleaasen P, Frøysaker T
Scand J Thorac Cardiovasc Surg. 1979;13(1):41-6. doi: 10.3109/14017437909101785.
The role of fresh autologous blood on haemostasis was studied in 30 patients undergoing aortic valve replacement. All the patients were extremely haemodiluted during the perfusion by using a non-haemic priming solution and withdrawal of 15% of the blood volume at the start of operation. In half of the patients, the autologous blood was retransfused immediately after the termination of perfusion. In the other half, donor blood was given in this period, while the retransfusion of autologous blood was delayed until three hours postoperatively. An increase of circulating platelets was found after the withdrawal of blood and replacement with double the amount of Ringer's acetate. Significantly less donor blood and plasma was transfused in the patients receiving early transfusion of autologous blood. An average reduction of 36% donor blood and 45% plasma was obtained. The blood losses were also less in these patients, but the differences were not significant.
对30例接受主动脉瓣置换术的患者研究了新鲜自体血在止血中的作用。所有患者在灌注期间均使用无血预充液进行极度血液稀释,并在手术开始时抽出15%的血容量。一半患者在灌注结束后立即回输自体血。另一半患者在此期间输注异体血,而自体血回输延迟至术后三小时。抽血并用两倍量的醋酸林格液替代后,循环血小板数量增加。接受早期自体血回输的患者输注的异体血和血浆明显减少。平均减少了36%的异体血和45%的血浆。这些患者的失血量也较少,但差异不显著。