Gibson T J, O'Dell R F, Cathcart R S, Rambo W M
South Med J. 1979 Apr;72(4):391-2. doi: 10.1097/00007611-197904000-00006.
The incidence of cholelithiasis and surgical risk of cholecystectomy in patients with sickle cell anemia is reviewed. Records of all patients with sickle cell disease currently attending the Medical University of South Carolina Hematology Clinic were reviewed. An oral cholecystogram has been part of the initial evaluation for the past year. The records of 16 patients having cholecystectomy from 1968 to 1977 were reviewed with regard to diagnostic studies, preoperative preparation, morbidity, and mortality. When the status of the gallbladder is known, the incidence of cholelithiasis is 67%. The morbidity of elective cholecystectomy was high (37%); there was one death. Cholecystectomy is not recommended for the discovery of asymptomatic gallstones because of the relatively poor surgical risk and short life expectancy of these patients.
对镰状细胞贫血患者的胆结石发病率及胆囊切除术的手术风险进行了综述。回顾了目前在南卡罗来纳医科大学血液学诊所就诊的所有镰状细胞病患者的记录。在过去一年中，口服胆囊造影一直是初始评估的一部分。回顾了1968年至1977年期间16例行胆囊切除术患者的诊断研究、术前准备、发病率和死亡率记录。当胆囊状况已知时，胆结石发病率为67%。择期胆囊切除术的发病率较高（37%）；有1例死亡。由于这些患者的手术风险相对较高且预期寿命较短，不建议因发现无症状胆结石而行胆囊切除术。
