有机磷和氨基甲酸酯类杀虫剂的比较代谢与选择性
Comparative metabolism and selectivity of organophosphate and carbamate insecticides.
作者信息
Hollingworth R M
出版信息
Bull World Health Organ. 1971;44(1-3):155-70.
Abstract
The comparative metabolism and toxicity of organophosphorus and carbamate insecticides are reviewed with the purpose of assessing our present ability to design new toxicants with improved selectivity. The occurrence of quantitative and qualitative differences in metabolism in vertebrates and insects is considered and an assessment is made of the role of metabolic activation and degradation in the complex interactions governing toxicity.
摘要
本文综述了有机磷和氨基甲酸酯类杀虫剂的比较代谢和毒性，旨在评估我们目前设计具有更高选择性的新型杀虫剂的能力。文中考虑了脊椎动物和昆虫在代谢方面存在的定量和定性差异，并对代谢活化和降解在复杂的毒性相互作用中所起的作用进行了评估。
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