Müller R P, Castrup W, Baumeister S, Burkhardtsmaier G
Strahlentherapie. 1979 Mar;155(3):149-53.
Therapeutic results from 134 cases with malignant tumors of the nasal cavity and paranasal sinuses are reported. Retrospective classification based on clinical and roentgenological findings was possible in 121 cases. 49 patients underwent primary radiation treatment by 60Co-teletherapy, 46 were exposed to postoperative irradiation. The mean 2-year survival rate considering all stages and all kinds of malignant tumors amounts to 52%, the 5-year survival rate to ca. 32%. The 5-year survival rate obtained by means of curative tumor doses was 59%. Recurrences of the tumor appeared in 58 cases (43%), most of them in the course of a year. The therapeutic control of local tumor disease and the possibilities of an early detection of recurrences, improved with the help of new diagnostic methods, must therefore be regarded as the essential problems. No generally approved clinical classification of tumors of the nasal cavity and paranasal sinuses is available as yet, and the comparison of therapeutic results from different authors thus is difficult.
报告了134例鼻腔和鼻窦恶性肿瘤的治疗结果。121例患者可根据临床和放射学检查结果进行回顾性分类。49例患者接受了60钴远距离治疗的初次放疗，46例接受了术后放疗。考虑到所有分期和各类恶性肿瘤，平均2年生存率为52%，5年生存率约为32%。通过根治性肿瘤剂量获得的5年生存率为59%。58例（43%）出现肿瘤复发，大多数在1年内复发。因此，借助新的诊断方法改善局部肿瘤疾病的治疗控制以及早期发现复发的可能性，必须被视为关键问题。目前尚无普遍认可的鼻腔和鼻窦肿瘤临床分类，因此不同作者的治疗结果比较困难。
