Platelet glycolysis in platelet storage I. The glycolytic enzymes.

Sixteen glycolytic enzymes were measured in essentially leukocyte-free platelets before storage and daily after room temperature storage or platelets as concentrates. Most of the glycolytic enzymes proved to be very stable to storage. Even the most severely affected enzymes, enolase, triosephosphate isomerase, and lactate dehydrogenase lost less than one-quarter of their enzyme activity. Depletion of glycolytic enzymes does not seem to be a major factor in the storage lesion of platelets.