Beutler E, Kuhl W
Transfusion. 1980 Jan-Feb;20(1):97-100. doi: 10.1046/j.1537-2995.1980.20180125051.x.
Platelet concentrates were prepared from blood collected in CPD, CPD-A1, and CPD-A3. CPD-A1 contains 1.25 times as much glucose as does CPD, and sufficient adenine to provide a final concentration of 0.25 mM; CPD-A3 contains twice as much glucose as does CPD, and sufficient adenine to provide a final concentration of 0.5 mM. The consumption of glucose and the production of lactate and pyruvate in the platelet concentrates during room temperature storage was not influenced by glucose or adenine concentration. There was no difference in the rates of fall of the pH of platelets collected in the three preservatives. However, the number of contaminating white blood cells had a significant effect on these parameters. It is suggested that minimizing the number of contaminating white blood cells in platelet preparations may prove to be an important factor in platelet preservation.
血小板浓缩物由采集于CPD、CPD - A1和CPD - A3抗凝剂中的血液制备而成。CPD - A1含有的葡萄糖量是CPD的1.25倍，且含有足够的腺嘌呤以提供最终浓度为0.25 mM；CPD - A3含有的葡萄糖量是CPD的两倍，且含有足够的腺嘌呤以提供最终浓度为0.5 mM。室温储存期间血小板浓缩物中葡萄糖的消耗以及乳酸和丙酮酸的产生不受葡萄糖或腺嘌呤浓度的影响。用这三种抗凝剂采集的血小板，其pH下降速率没有差异。然而，污染白细胞的数量对这些参数有显著影响。有人提出，尽量减少血小板制剂中污染白细胞的数量可能是血小板保存中的一个重要因素。
