联合血小板白细胞去除术：一种从单个供体制备单独血小板和粒细胞-血小板单位的技术。

Combined platelet-leukapheresis: a technique for preparing separate platelet and granulocyte-platelet units from single donors.

作者信息

Strauss R G, Goedken M M, Maguire L C, Koepke J A, Thompson J S

出版信息

Transfusion. 1979 Mar-Apr;19(2):206-9. doi: 10.1046/j.1537-2995.1979.19279160296.x.

DOI:10.1046/j.1537-2995.1979.19279160296.x

Abstract

One donor can provide separate platelet and granulocyte-platelet units that have the potential to fulfill the needs of two recipients. Combined platelet and leukapheresis were performed in the presence of hyddroxyethyl starch and citrate employing the Haemonetics Model 30 Blood Separator. Platelets and granulocytes were separated subsequently by centrifugation and two individual units were prepared for transfusion. The platelet units contained a mean of 4.4 x 10(11) platelets/unit and were nearly devoid of leukocytes. The combined granulocyte-platelet units contained a mean of 7.38 x 10(9) neutrophils/unit and 3.06 x 10(11) platelets/unit. Thus two separate units containing sufficient numbers of cells for transfusion can be obtained from pheresis of one donor.

摘要

一名捐献者可以提供单独的血小板单位和粒细胞 - 血小板单位，有可能满足两名受者的需求。在羟乙基淀粉和枸橼酸盐存在的情况下，使用Haemonetics 30型血液分离机进行血小板和白细胞单采联合采集。随后通过离心分离血小板和粒细胞，并制备两个单独的单位用于输血。血小板单位平均每单位含有4.4×10¹¹个血小板，几乎没有白细胞。粒细胞 - 血小板联合单位平均每单位含有7.38×10⁹个中性粒细胞和3.06×10¹¹个血小板。因此，从一名捐献者的单采中可以获得两个单独的、含有足够数量可用于输血细胞的单位。