Moosa A, Dubowitz V
Arch Dis Child. 1971 Dec;46(250):852-4. doi: 10.1136/adc.46.250.852.
The ulnar and posterior tibial conduction velocities were measured in 6 untreated and 3 treated cretins. In 4 of the untreated patients, the conduction velocity of both nerves was slower than normal; in 1 patient the ulnar and in the other the posterior tibial nerve conduction velocity was slower than normal. There was a close agreement between bone age and the age corresponding to the slow conduction velocities. The 3 treated cretins all had normal posterior tibial conduction velocities, while the ulnar conduction velocity was normal in one, slower in another, and faster than normal in the third. The slow nerve conduction velocity in cretins probably reflects a delay in maturation of the peripheral nerves. Nerve conduction velocity measurement may be a useful screening test in suspected congenital hypothyroidism, and may also prove of value in assessing response to therapy.
对6名未经治疗和3名已治疗的克汀病患者测量了尺神经和胫后神经的传导速度。在4名未经治疗的患者中，两条神经的传导速度均低于正常；在1名患者中尺神经传导速度低于正常，在另1名患者中胫后神经传导速度低于正常。骨龄与对应于缓慢传导速度的年龄之间存在密切一致性。3名已治疗的克汀病患者胫后神经传导速度均正常，而尺神经传导速度在1名患者中正常，在另1名患者中较慢，在第3名患者中高于正常。克汀病患者神经传导速度缓慢可能反映了周围神经成熟延迟。神经传导速度测量可能是疑似先天性甲状腺功能减退症的一项有用筛查试验，在评估治疗反应方面也可能有价值。
